Bisindolylmaleimide XI hydrochloride

目录号：SY-110086

Bisindolylmaleimide XI hydrochloride(Ro 32-0432)是一种口服活性的泛PKC抑制剂，对 PKCα、PKCβI、PKCβII、PKCγ 具有抑制作用（IC50=9/28/31/37/108 nM）。

¥2310.00

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Epsilon-V1-2

目录号：SY-110085

Epsilon-V1-2 是蛋白激酶 C ε（PKCε）的特异性抑制剂。Epsilon-V1-2 被用于卵巢衰老、人颗粒细胞凋亡、脑缺血-再灌注损伤、脑发育、肝细胞胰岛素信号转导以及缺血条件下神经元细胞死亡等相关研究。研究表明，Epsilon-V1-2 能够有效降低 PKCε 的活性，从而促进对线粒体动力学、钙超载、AKT 激活、脑萎缩、胰岛素抵抗及铁死亡等调控通路的深入解析。Epsilon-V1-2 在卒中、SHORT 综合征、肝脂肪变性及脑损伤等疾病模型中显示出显著的治疗相关性。

¥1615.00

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Protein Kinase C (19-31)

目录号：SY-110084

Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC) derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as a protein kinase C substrate peptide.

¥641.00

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PS432

目录号：SY-110083

PS432 is an allosteric inhibitor of atypical PKCs. PS432 targets the PIF-pocket resulting in significantly reduce tumor growth without side effects in mouse xenograft model.

¥968.00

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Dihydrosphingosine

目录号：SY-110115

Dihydrosphingosine is a Protein kinase C inhibitor.

¥1694.00

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PKC-theta inhibitor 1

目录号：SY-110114

PKC-theta inhibitor 1 is an inhibitor of PKCθ (Ki of 6 nM)

¥2442.00

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Bisindolylmaleimide I HCl

目录号：SY-110113

Bisindolylmaleimide I HCl is a specific ATP-competitive PKC inhibitor.

¥363.00

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PKC β pseudosubstrate

目录号：SY-110112

Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM). Consists of amino acids 19 - 31 of PKC pseudosubstrate domain linked by a disulphide bridge to a cell permeabilisation Antennapedia domain vector peptide. The Antennapedia pep

¥2310.00

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(-)-Indolactam V

目录号：SY-110111

(-)-Indolactam V is a PKC activator (Kis: 3.36 nM, 1.03 μM for η-CRD2 , γ-CRD2). (-)-Indolactam V also has the Kds are 5.5 nM (η-C1B), 7.7 nM (ε-C1B), 8.3 nM (δ-C1B), 18.9 nM (β-C1A-long), 20.8 nM (α-C1A-long), 137 nM (β-C1B), 138 nM (γ-C1A), 213 nM (γ-C1

¥1386.00

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