Tadalafil-D3

目录号：SY-128109

Tadalafil-D3是Tadalafil (T1398)的氘代化合物。Tadalafil的CAS号为171596-29-5。Tadalafil是一种PDE5抑制剂，IC50为 1.8 nM。

¥1506.00

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Ophiobolin A

目录号：SY-128111

Ophiobolin A is a fungal metabolite and a phytotoxin and is an effective and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase (IC50: 9 μM). Ophiobolin A also has antimicrobial and anticancer activity.

¥5692.00

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ITI-214 free base

目录号：SY-128113

ITI-214 free base is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM).

¥1506.00

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PF-04671536

目录号：SY-128115

PF-04671536 is a highly potent and selective inhibitor of phosphodiesterase 8B (PDE8B) phosphodiesterase 8A (PDE8A). In primary human pancreatic islets, PF-04671536 increases insulin secretion in a glucose-dependent manner.

¥5692.00

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5,7-Dichloropyrazolo[1,5-a]pyrimidine

目录号：SY-128117

5,7-Dichloropyrazolo[1,5-a]pyrimidine (fragment 5) 是一种用于研究精神分裂症的吡唑并嘧啶磷酸二酯酶 10A (PDE10A) 抑制剂，抑制常数 Ki 为 24 μM。

¥345.00

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PDE12-IN-1

目录号：SY-128119

PDE12-IN-1 is a powerful and specific inhibitor of PDE12, exhibiting a pIC 50 value of 9.1 for enzyme inhibition. It effectively enhances levels of 2′,5′-linked adenylate polymers (2-5A), with a pEC 50 value of 7.7. Additionally, PDE12-IN-1 demonstrates antiviral activity.

¥1012.00

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PDE12-IN-3

目录号：SY-128121

PDE12-IN-3 is an inhibitor of phosphodiesterase 12 (PDE12) (pXC50 of 7.68),with antiviral activity.

¥2875.00

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L-6355

目录号：SY-128123

L-6355 is an agent of bioactive chemicals.

¥10086.00

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NPD-1335

目录号：SY-128125

NPD-1335 (Benzyl alkynamide 37) 一种有效的布氏锥虫磷酸二酯酶 B1 (TbrPDEB1) 抑制剂，具有针对布氏锥虫寄生虫的亚微摩尔活性。 NPD-1335 (Benzyl alkynamide 37) 显示出改善的细胞毒性谱。 NPD-1335 (Benzyl alkynamide 37) 会增加细胞内 cAMP 水平，导致细胞周期和细胞死亡的改变。

¥828.00

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