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ERX-41
目录号:SY-127242
ERX-41是一种口服活性的立体特异性小分子,靶向溶酶体酸性脂肪酶A (LIPA)。该化合物通过诱导内质网(ER)应激从而导致细胞死亡,这一作用表明ERX-41功能独立于LIPA,但依赖于其在内质网的定位。ERX-41主要用于实体瘤靶向研究。
¥1035.00
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(1S)-(+)-Camphor-10-sulphonic acid
目录号:SY-127243
(1S)-(+)-Camphor-10-sulphonic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66968,CAS号为 3144-16-9。
¥1667.00
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URB754
目录号:SY-127244
URB754 is a potent and noncompetitive inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 200 nM for the recombinant rat brain enzyme. However, it does not inhibit human recombinant, rat brain, or mouse brain MAGL at concentrations up to 100 μM. There is evidence that the MAGL inhibitory activity of URB754 may be attributed to the impurity bis(methylthio)mercurane (IC50 = 11.9 nM for rat recombinant MAGL) that is found in commercial preparations. URB754 inhibits rat brain fatty acyl amide hydrolase (FAAH) with an IC50 value of 32 μM and binds weakly to the rat central cannabinoid (CB1) receptor with an IC50 value of 3.8 μM. It does not inhibit COX-1 or COX-2 at concentrations up to 100 μM. Inhibition of MAGL hydrolysis of 2-arachidonoyl glycerol (2-AG) is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management.
¥3312.00
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PF-06795071
目录号:SY-127245
PF-06795071 is an effective and selective covalent inhibitor of MAGL (IC50: 3 nM).
¥5336.00
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Ciwujianoside D2
目录号:SY-127246
Ciwujianoside D2 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126336,CAS号为 114892-57-8。
¥1932.00
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Hericenone D
目录号:SY-127247
Hericenone D 是一种天然产物,可用作天然产物对照品,用于生命科学相关领域的研究,其产品编号为 TN8547。
¥4266.00
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HSL-IN-5
目录号:SY-127248
HSL-IN-5(Example21)是一种激素敏感性脂肪酶(HSL,Hormone-Sensitive Lipase)抑制剂,IC50的值为0.2 μM,可用于研究糖尿病。
¥1932.00
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Acanthopanaxoside A
目录号:SY-127249
Acanthopanaxoside A 为三萜类皂苷化合物,能够抑制胰腺脂肪酶 (lipase) 活性。
¥4266.00
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Ciwujianoside C4
目录号:SY-127250
Ciwujianoside C4是一种来源于刺五加的皂苷类化合物,在体外条件下可增强胰腺脂肪酶(Pancreatic lipase)的活性,用于消化酶调控相关研究。
¥2656.00
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