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17(S)-HpDHA
目录号:SY-127530
17(S)-HpDHA为主要由15-Lipoxygenase(LOX)同工酶:h15-LOX-1和h15-LOX-2与二十二碳六烯酸(DHA)反应生成。该化合物通过变构负向调控环氧化物合成,且能够抑制血小板聚集,其EC50值约为1μM。
¥345.00
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Lobaric acid
目录号:SY-127531
Lobaric acid is a depsidone metabolite that has been isolated from Stereocaulon lichen species with antioxidant, antiproliferative, antiviral, and enzyme inhibitory activites. It scavenges superoxide radicals in a cell-free assay (IC50 = 97.9 μmol) and inhibits proliferation in a panel of leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic, and lung cancer cell lines (EC50s = 15.2-63.9 μg/ml). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC50 = 0.87 μM for the human recombinant enzyme) and production of 12(S)-HETE (Item No. 34570) by 12(S)-lipoxygenase (IC50 = 28.5 μM). In vivo, lobaric acid (250 μM) decreases lesion number, but not lesion diameter, in tobacco leaves infected with tobacco mosaic virus (TMV).
¥575.00
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(±)15-HEDE
目录号:SY-127532
(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid. There are no reports in the literature of biological activity associated with (±)15-HEDE.
¥1150.00
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15(S)-HEDE
目录号:SY-127533
15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 μM.
¥2070.00
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Enazadrem
目录号:SY-127534
Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.
¥345.00
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Zileuton sodium
目录号:SY-127535
Zileuton sodium是一种选择性和可逆的5-脂氧合酶(5-LOX)抑制剂,能够抑制LTB4的合成,可显著降低花生四烯酸诱导的小鼠耳部水肿(ED50 = 31 mg/kg),可用于研究炎症。
¥575.00
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Caffeoylcalleryanin
目录号:SY-127536
Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.
¥1150.00
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Acetohexamide (Standard)
目录号:SY-127537
Acetohexamide (Standard) 是 Acetohexamide 的标准品,适用于定量分析、质量控制及生化实验等相关研究。Acetohexamide (Acetohexamid) 是磺脲类试剂,可刺激胰腺分泌胰岛素,能够用于 2 型糖尿病的相关研究。
¥2070.00
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5-Lipoxygenase-In-1
目录号:SY-127538
5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.
¥29.00
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