NNC45-0781 is a tissue-selective partial-agonist of estrogen.

GNE-274, a non-degrader compound structurally similar to GDC-0927 (an ER degrader), serves as a partial ER agonist in breast cancer cell lines without triggering ER turnover. Notably, GNE-274 enhances chromatin accessibility at ER-DNA binding sites, unlike GDC-0927. Acting as a potent inhibitor of the ER-ligand binding domain (LBD), GNE-274 exhibits potential for cancer research purposes.

Erb-196 is an estrogen receptor-receptor agonist with non-steroidal selectivity.

Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.

Pure antiestrogen that downregulates estrogen receptor expression

DK1 是有效的雌激素相关受体调节剂。DK1 影响 ERRα 受体的活性，具有降低血糖的能力。DK1 显示出研究糖尿病的潜力。

GNE-502 is an orally active and potent estrogen receptor (ER) degrader, specifically designed for research on breast cancer.

Nitromifene is the estrogen receptor antagonist.

GDC-0927 is a novel,non-steroidal, potent, orally bioavailable, selective estrogen receptor antagonist.