400-0755-639
联系微信客服
最新产品
三叶新科每月上新,持续为科研人员提供新颖性研究工具,助力科研创新与突破。
首页 最新产品
6β-hydroxy Dexamethasone
目录号:SY-112361
6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans., The formation of 6-hydroxy dexamethasone metabolites is species-specific, with hamsters producing the highest amount. In rats, dexamethasone hydroxylation is sex-specific, with male rats producing metabolites in similar ratios to humans and female rats producing fewer hydroxylated metabolites than male rats.
¥2300.00
查看详情
5α-Tetrahydrocorticosterone
目录号:SY-112362
5α-Tetrahydrocorticosterone (5α-HB) 是一种内源性类固醇, 作为糖皮质激素受体 (glucocorticoid receptor) (GR) 的激动剂,同时是 Corticosterone 的代谢产物。这种化合物在体内是有效的局部抗炎剂。5α-Tetrahydrocorticosterone 通过降低大鼠肝细胞中代谢物与糖皮质激素受体-皮质酮及其 5α-还原代谢物的结合,显示出Kd值为 268 nM。在炎症性皮肤疾病的研究中,5α-Tetrahydrocorticosterone 具有重要应用。
¥1725.00
查看详情
LEO 134310
目录号:SY-112363
LEO 134310 是一种选择性非甾体糖皮质激素受体 (GR) 激动剂,优化用于局部治疗。LEO 134310 在 GR 结合试验中显示出高亲和力(EC50为 14 nM)。LEO 134310 可用于皮肤病。
询价
查看详情
ACTH (6-24) (human)
目录号:SY-112364
ACTH (6-24) (human)(腎上腺皮質激素(6-24))是腎上腺皮質激素的片段。該化合物作為ACTH (1-39) 和 ACTH (5-24) 引起的類固醇生成的競爭性抑制劑,具有相應的Kd值分別為13.4和3.4nM。此外,ACTH (6-24) (human) 能夠抑制 hPTH 1-34 所誘導的皮質酮產生以及cAMP的累積。
询价
查看详情
Hydrocortisone sodium succinate
目录号:SY-112365
Hydrocortisone sodium succinate is a glucocorticoid which is used to alleviate allergic reactions, particularly those of the skin and gums.
¥142.00
查看详情
AL-438
目录号:SY-112366
AL-438 is a non-steroidal selective glucocorticoid receptor modulator.
询价
查看详情
Dagrocorat hydrochloride
目录号:SY-112367
PF-0251802 HCl is a bio-active chemical.
¥2618.00
查看详情
Rimexolone
目录号:SY-112368
Rimexolone is a glucocorticoid steroid used to treat inflammation in the eye.
¥3231.00
查看详情
Hydrocortisone-d4
目录号:SY-112369
Hydrocortisone-d4 是 Hydrocortisone 的氘代化合物。Hydrocortisone 的 CAS 号为 50-23-7。Hydrocortisone 是肾上腺皮质分泌的糖皮质激素。
¥2656.00
查看详情