ent-(+)-verticilide is an effective and specific inhibitor of cardiac ryanodine receptor (RyR2) calcium release channels, demonstrating antiarrhythmic properties. It suppresses RyR2-mediated diastolic Ca2+ leak and shows greater potency and a unique action mechanism compared to Dantrolene and Tetracaine. ent-(+)-verticilide serves as a valuable tool for exploring the therapeutic potential of addressing RyR2 hyperactivity in cardiac and neurological conditions [1].

Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.

AS252424 是一种有效的、选择性的 PI3Kγ 抑制剂，其 IC50=30±10 nM。

Katacalcin (PDN 21) is a potent peptide that lowers plasma calcium.

Acetylcholine-D4 chloride是Acetylcholine chloride (T1221)的氘代物。Acetylcholine chloride (ACh chloride)是一种神经递质，同时也是一种高效的胆碱能 (cholinergic)激动剂。它通过刺激烟碱乙酰胆碱受体 (nAChRs)来调节多巴胺能 (DAergic)神经元的活性。此外，Acetylcholine chloride 能在体外抑制 p53 突变肽的聚集。

Amlodipine-D4 Maleate (Racemic)是Amlodipine Maleate (Racemic) (T21263)的氘代化合物。Amlodipine Maleate (Racemic)的CAS号为88150-47-4。Amlodipine maleate是一种具有口服活性的二氢吡啶类钙通道阻滞剂，通过阻滞电压依赖性L型钙通道，从而抑制钙离子内流。Amlodipine maleate可用于研究高血压和癌症。