Prodigiosin hydrochloride, a red pigment, is a bioactive secondary metabolite produced by bacteria. It exhibits potent proapoptotic activity and functions as an inhibitor of the Wnt/β-catenin pathway. Additionally, this compound possesses antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties.

AS1134900 是一种高选择性的、非竞争性的、变构的 NADP+依赖的苹果酸酶 1 (ME1) 抑制剂。

GB1874是一种靶向β-cat-TCF4 PPI的Wnt通路的抑制剂，影响wnt依赖性结直肠癌(CRC)细胞的增殖和干细胞性，在体内抑制HCT116肿瘤异种移植物的生长。

8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction, it may be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated transcriptional activation of NF-κB and

β-catenin-IN-6是一种针对Wnt/β-catenin(典型的wingless相关整合位点)通路的抑制剂，能够抑制人类结直肠癌细胞的增殖，并在β-catenin/RK3E小鼠模型上展现出效果。

PTK7/β-catenin-IN-6 (Compound 03653) 作为一类抑制PTK7/β-catenin相互作用的化合物，能有效地抑制Wnt信号通路，对结直肠癌 (CRC) 具有抗癌效果。