Aurothioglucose is a active-site TrxR1 inhibitor.

Avasopasem manganese is a drug candidate of superoxide dismutase mimetic.

AD 0261 is a radical scavenger. It has a strong inhibitory action on the generation of lipid peroxides and superoxide anions.

RIDR-PI-103 是活性氧 (ROS) 诱导的药物释放前药，含有与泛 PI3K 抑制剂 (PI-103) 连接的自环化部分。在 MDA-MB-361 和 MDA-MB-231 细胞中，Doxorubicin 和 RIDR-PI-103 表现出协同的抑制癌细胞增殖作用。

9(Z),11(E),13(E)-Octadecatrienoic Acid ethyl ester (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ. In DLD-1 cells supplemented with α-ESA, apoptosis was induced via lipid peroxidation with an EC50 of 20 μM. It also inhibits DNA polymerases and topoisomerases with IC50s ranging from ~5-20 μM for different isoforms of the enzymes. α-ESA ethyl ester is a neutral, more lipid soluble form of the free acid.

QM385 is a potent inhibitor of sepiapterin reductase (SPR)(IC50 of 1.49 nM).