HIF-1α-IN-3

目录号：SY-127023

HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1].

¥285.00

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HIF-PHD-IN-1

目录号：SY-127024

HIF-PHD-IN-1 is a pharmacological compound that acts as an orally active inhibitor of the hypoxia-inducible factor prolyl hydroxylase domain (HIF-PHD), displaying an IC50 of 54 nM for hHIF-PHD2. Its potential as a therapeutic agent for renal anemia is highly promising.

¥784.00

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HIF-1/2α-IN-2

目录号：SY-127026

HIF-1/2α-IN-2是一种靶向缺氧诱导因子1α和2α（HIF-1α和HIF-2α）的选择性抑制剂，通过抑制铁硫簇组装蛋白2（ISCA2）活性，诱导细胞铁缺乏状态，进而减少HIF-2α的合成，最终触发铁死亡。HIF-1/2α-IN-2广泛应用于肿瘤生物学、代谢调控及缺血相关研究。

¥345.00

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Steppogenin

目录号：SY-127027

Steppogenin exhibits significant tyrosinase inhibition activity, ;it also shows strong mushroom tyrosinase inhibitory activity with IC(50) values lower than 50 microM, more potent than kojic acid (IC(50) = 71.6 microM), a well-known tyrosinase inhibitor.

¥780.00

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TAT-cyclo-CLLFVY

目录号：SY-127028

Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-1α, but not HIF-2α, with HIF-1β (IC50 = 1.3 μM). Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast cance

¥2748.00

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HIF-2α-IN-9

目录号：SY-127030

HIF-2α-IN-9（compound 35r）为HIF-2α抑制剂，能够抑制VEGF-A（IC50=305 nM），影响肿瘤细胞生长基因表达并促进巨噬细胞介导的肿瘤免疫反应。

¥759.00

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