Gemcabene calcium , a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) andexerting anti-inflammatory activity, lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP).

Campestanol is a natural plant sterol from Brassica campestris.

LY 295427 is a bioactive chemical.

ANG1005是一种紫杉烷类衍生物，采用三个紫杉醇分子与Angiopep-2共价结合而成的脑穿透肽活性分子偶联物。此化合物设计用于利用低密度脂蛋白受体相关蛋白（LRP1）运输系统，穿透血脑和血脑脊髓屏障，进而作用于恶性细胞。

The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall. CAY10487 inhibits formation of fatty streak lesions of the thoracic aorta in high cholesterol-fed rabbits without affecting plasma lipid profiles or significantly inhibiting ACAT-1 or ACAT-2 activity. The percent area occupied by the atherosclerotic lesion in rabbits supplemented with 0.05% CAY10487 in the diet was 16.1% compared to 53.5% in control rabbits. CAY10487 also exhibits antioxidant activity, inhibiting copper-mediated oxidation of low-density lipoprotein by about 75% at a concentration of 2 μM.

Luteolin-7-O-β-D-glucuronide methyl ester 是一种具抗氧化活性的黄酮类化合物。在 NBT 超氧化物清除试验中，Luteolin-7-O-β-D-glucuronide methyl ester 显示出显著的抗氧化能力，IC50为 3.05 μg/mL。此外，该化合物可有效抑制 Cu2+诱导的 LDL 氧化，IC50值为 71.13 μg/mL。