GGACK (H-Glu-Gly-Arg-CMK) 是一种不可逆的底物模拟物，专门作为尿激酶型纤溶酶原激活剂 (uPA) 的丝氨酸蛋白酶抑制剂。

Pomolic acid 28-O-beta-D-glucopyranosyl ester is a natural product

UK-122 is a potent and selective uPA inhibitor (Ki = 20 nM). The IC(50) of UK122 in a cell-free indirect uPA assay is 0.2 micromol/L. UK122 showed little cytotoxicity against CFPAC-1 cells (IC(50) > 100 micromol/L) but significantly inhibited the migratio

CDE-096 是一种高效的纤溶酶原激活物抑制剂-1 抑制剂，可在纳摩尔水平阻止 PAI-1 介导的组织型纤溶酶原激活物和尿激酶型纤溶酶原激活物失活，同时对糖基化及多物种来源的 PAI-1 保持活性，为纤溶与血栓调控的转化研究提供了支持。

ARN1468 (compound 5) is a highly effective orally active inhibitor of serpins. Inhibition of serpins activity by ARN1468 enables release of proteases, thereby reducing prion accumulation. ARN1468 demonstrates pronounced anti-prion effects in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC 50 values of 8.64, 19.3, 11.2, and 6.27 μM [1].

(+)-Geodin is a fungal metabolite. It increases the fibrinolytic activity of bovine aortic endothelial cells (BAECs) when used at concentrations ranging from 50 to 150 μM. (+)-Geodin (1-100 μg/ml) also increases 2-deoxyglucose uptake by rat adipocytes.