α-Glucosidase (α-D-Glucosidase) is a carbohydrate hydrolyzing enzyme that catalyzes the release of α-glucose from the non-reducing end of the substrate. It plays a vital role in facilitating glucose absorption by the small intestine. Inhibiting α-Glucosidase effectively manages non-insulin-dependent diabetes mellitus (NIDDM).

Lucialdehyde C (Lucidal) exhibits potent cytotoxicity against LLC, T-47D, Sarcoma 180, and Meth-A tumor cells with ED(50) values of 10.7, 4.7, 7.1, and 3.8 microg/ml, respectively.

Homonojirimycin is an alpha-glucosidase inhibitor.

Clervonafusp alfa (VAL-1221) 作为一种融合蛋白，针对胞浆及溶酶体糖原进行靶向。该化合物结合了穿透细胞的抗体Fab部分与重组人酸性葡萄糖苷酶 (rhGAA)，通过核苷转运体ENT-2进入细胞质，再利用甘露糖-6-磷酸受体(M6PRs)导向溶酶体。主要应用于晚发型庞贝病的研究领域。

Valienamine为α-葡萄糖苷酶抑制剂，为众多天然糖苷酶抑制剂，包含用于作物保护的validamycin A及治疗糖尿病的阿卡波糖，的关键活性成分。

3α-Akebonoic acid is a natural product isolated from Holboellia coriacea Diels with antitumor activity.