Maytansinoid B

目录号：SY-100669

Maytansinoid B 是一种ADC Cytotoxin，用于形成与抗体结合的Antibody-Drug Conjugates (ADCs)。它是一种抗有丝分裂剂，能够结合微管蛋白并阻断其组装，诱导细胞周期在G2/M阶段停滞，进而触发细胞凋亡(apoptosis)。

¥2852.00

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Duocarmycin GA

目录号：SY-100670

Duocarmycin GA, an antibody drug conjugate (ADC) toxin and a DNA alkylating agent, effectively targets and binds in the minor groove of DNA. It is particularly potent against multi-drug resistant cell lines, offering a strategic approach in combating resistance.

¥20240.00

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7-MAD-MDCPT

目录号：SY-100671

7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs).

¥2300.00

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Tubulysin

目录号：SY-100672

Tubulysin family are originally isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis, and are potent microtubule destabilizing agents.

¥7392.00

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Gly-7-MAD-MDCPT

目录号：SY-100673

Gly-7-MAD-MDCPT 是一种抗癌剂。Gly-7-MAD-MDCPT 是一种喜树碱 (Camptothecin) 化合物，对多种癌细胞有细胞毒性，IC50为 10-1000 nM。

¥6681.00

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PF-06380101

目录号：SY-100674

PF-06380101 is an auristatin microtubule inhibitor and is a cytotoxic Dolastatin 10 analogue. When compared to other synthetic auristatin analogues that are used in the preparation of ADCs, PF-06380101 displays excellent potencies in tumor cell proliferat

¥1232.00

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