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(±)10(11)-DiHDPA
目录号:SY-124407
(±)10(11)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid . It has been shown to inhibit VEGF-induced angiogenesis in mice and may have additional anti-inflammatory and anti-tumor effects.
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Reduced Haloperidol
目录号:SY-124408
Reduced haloperidol is an active metabolite of haloperidol . It is formed via reduction of haloperidol by ketone reductase. Reduced haloperidol inhibits radioligand binding to sigma-1 and dopamine D2 receptors (Kis = 1.4 and 31 nM, respectively) and stimulates brain-derived neurotrophic factor (BDNF) secretion from CCF-SSTG1 and U87MG astrocytic glial cells. It also inhibits norepinephrine, dopamine, and serotonin (5-HT) reuptake (Kis = 21, 25, and 33 μM, respectively, in COS-7 cells expressing the human transporters). Reduced haloperidol (0.5 mg/kg) increases latency to paw withdrawal in mouse models of capsaicin- but not force-induced mechanical hypersensitivity.
¥3277.00
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(Rac)-3′-Hydroxy simvastatin
目录号:SY-124409
(Rac)-3′-Hydroxy simvastatin 是一种 Simvastatin 代谢物。Simvastatin 是一种竞争性的 HMG-CoA 还原酶抑制剂,Ki 值为 0.2 nM。
¥3795.00
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Quetiapine sulfoxide dihydrochloride
目录号:SY-124410
Quetiapine sulfoxide dihydrochloride is a main Quetiapinem metabolite. Quetiapine is a agonist of 5-HT receptors and a antagonist of dopamine receptor.Quetiapine is a second-generation antipsychotic.
¥805.00
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Mono(5-carboxy-2-ethylpentyl) phthalate
目录号:SY-124411
Mono(5-carboxy-2-ethylpentyl) phthalate (MECPP)是Di-(2-ethylhexyl) phthalate (DEHP)的一种代谢产物,后者为硬质聚氯乙烯(PVC)中添加的主要增塑剂,以提升其柔韧性、耐温性、光学透明性、强度和抗扭结性。
¥4830.00
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Venetoclax N-oxide
目录号:SY-124412
Venetoclax N-oxide 是 Venetoclax 的杂质。Venetoclax (ABT-199; GDC-0199) 是一种高效,选择性的和口服有效的Bcl-2抑制剂,Ki 小于0.01 nM。
¥1311.00
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