2-PyriMidinaMine, 4-[3-fluoro-5-(4-Morpholinyl)phenyl (Compound 9l) 是一种ATP竞争型的JNK(c-jun-N-terminal kinase)抑制剂，对JNK1和JNK3的IC50为0.099μM和0.148μM，具有可穿透血脑屏障的优点。2-PyriMidinaMine, 4-[3-fluoro-5-(4-Morpholinyl)phenyl能够抑制c-jun磷酸化和ROS生成，可用于研究神经退行性疾病。

Iso-AS601245 trifluoroacetate是AS601245的异构体，AS601245是一种ATP竞争性和选择性的JNK抑制剂，对hJNK1/2/3的IC50=150/220/70 nM，具有神经保护作用。

Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also has potential chemosensitizing activity, it may be candidates for developing novel adjuvant an

8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM.

JD118是一种JNK抑制剂，能够抑制JNK1的活性以及cJun (1 - 135) 的表达。

CMX-8933 是一种由8个氨基酸组成的肽段，源自金鱼脑神经营养因子的室管膜蛋白。该化合物能够提升c-Jun N-末端激酶 (JNK) 的活性，促进JNK和c-Jun蛋白的磷酸化，并增加c-Jun及c-Fos mRNA在细胞中的水平。CMX-8933 主要用于探索室管膜蛋白在神经可塑性、学习、记忆形成和神经再生中的功能。