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MAL3-101
目录号:SY-109650
MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).
¥5405.00
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MAO A/HSP90-IN-2
目录号:SY-109651
MAO A/HSP90-IN-2(compound 4-C)是一种针对HSP90和MAO A的双重抑制剂,显示出分别对这两种酶有0.016 μM和4.58 μM的IC50值。该化合物能够上调HSP70,降低HER2和磷酸化AKT的表达,同时能减少GL26细胞中由IFN-γ诱导的PD-L1表达增加。此外,MAO A/HSP90-IN-2能够抑制对Temozolomide敏感或耐药的胶质母细胞瘤(GBM)、结肠癌、白血病和非小细胞肺癌细胞的生长,并可能有助于阻止肿瘤逃避免疫监控。
询价
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MK2-IN-1
目录号:SY-109652
MK2-IN-1 is a potent and selecitve MAPKAPK2(MK2) inhibitor(IC50=0.11 uM) with a non-ATP competitive binding mode.
¥368.00
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Palmitic acid-13C2
目录号:SY-109653
Palmitic acid-13C2 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.
¥575.00
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Neoantimycin
目录号:SY-109654
Neoantimycin is an antibiotic originally isolated from S. orinoci that has slight antifungal activity. It is structurally similar to antimycin despite being produced by an unrelated species of Streptomyces. The biosynthetic pathway of neoantimycin has been determined and active analogs discovered.
¥6072.00
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SEW84
目录号:SY-109655
SEW84 是 Aha1 刺激的 Hsp90(ASH) ATP 酶活性的抑制剂。SEW84 抑制 Aha1 刺激的 Hsp90(ASH) 活性,IC50值为 0.3 μM。SEW84 可用于蛋白质沉积疾病的研究。
¥984.00
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