Gosuranemab(BIIB092)是一种靶向N端tau的人源化单克隆抗体，抑制病理性tau蛋白的扩散和聚集，可用于阿尔茨海默病。

BSc3094 is a potent Tau aggregation inhibitor that demonstrates the potential for Alzheimer's disease (AD) research.

Posdinemab为一种针对微管相关蛋白tau (MAPT)的人源化IgG1κ抗体。

PM534是一种微管蛋白(tubulin)靶向剂，抑制微管蛋白组装，其IC50值为0.8 ~ 3.2 nM。PM534结合微管蛋白的秋水仙碱位点，具有高抗肿瘤活性。

Hydromethylthionine, also known as LMTM and Leucomethylene Blue, is a apotent tau aggregation inhibitor for the treatment of Alzheimer's disease (AD) and frontotemporal dementia. Hydromethylthionine showed pharmacological activity on brain structure and function as both monotherapy and as an add-on to symptomatic treatment in certain patients with Alzheimer’s disease.

Sagopilone is a fully synthetic low-molecular-weight epothilone with potential antineoplastic activity. Sagopilone binds to tubulin and induces microtubule polymerization while stabilizing microtubules against depolymerization, which may result in the inhibition of cell division, the induction of G2/M arrest, and apoptosis. The agent is not a substrate for the P-glycoprotein (P-gp) efflux pump and so may exhibit activity in multidrug-resistant (MDR) tumors. The epothilone class of metabolites was originally isolated from the myxobacterium Solangium cellulosum.