PKM2-IN-3

目录号：SY-128155

PKM2-IN-3 is a potent PKM2 kinase inhibitor, displaying an IC 50 value of 4.1 μM. The compound effectively suppresses PKM2-mediated glycolysis and NLRP3 activation, thereby exerting an anti-neuroinflammatory effect.

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PDE12-IN-3

目录号：SY-128121

PDE12-IN-3 is an inhibitor of phosphodiesterase 12 (PDE12) (pXC50 of 7.68),with antiviral activity.

¥2875.00

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Metaxalone

目录号：SY-128137

Metaxalone (Methaxalonum) 具有肌肉松弛作用。

¥2990.00

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Ophiobolin A

目录号：SY-128111

Ophiobolin A is a fungal metabolite and a phytotoxin and is an effective and irreversibly inhibitor of calmodulin-activated cyclic nucleotide phosphodiesterase (IC50: 9 μM). Ophiobolin A also has antimicrobial and anticancer activity.

¥5692.00

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NPD10084

目录号：SY-128165

NPD10084 是一种靶向丙酮酸激酶 M2 亚型（PKM2）的抑制剂。NPD10084 通过作用于 PKM2 的非糖酵解信号功能，干扰 PKM2 与 β-catenin 或 STAT3 之间的蛋白-蛋白相互作用来抑制下游信号传导，从而对多种结直肠癌细胞系表现出抗增殖活性（体外 IC₅₀范围为 0.8–1.9 μM）。

¥1311.00

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PDE12-IN-1

目录号：SY-128119

PDE12-IN-1 is a powerful and specific inhibitor of PDE12, exhibiting a pIC 50 value of 9.1 for enzyme inhibition. It effectively enhances levels of 2′,5′-linked adenylate polymers (2-5A), with a pEC 50 value of 7.7. Additionally, PDE12-IN-1 demonstrates antiviral activity.

¥1012.00

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