Metaxalone-D6 is intended for use as an internal standard for the quantification of metaxalone by GC-or LC-MS. Metaxalone (T1610) is a skeletal muscle relaxant. It inhibits the proliferation of,and induces apoptosis in,RAW 264.7 cells in vitro when used at concentrations ranging from 1 to 100 µM. Metaxalone (T1610)also reduces LPS-induced increases in COX-1,COX-2,and NF-kB levels and inhibits LPS-induced production of TNF-α,IL-6,and prostaglandin E2 in RAW 264.7 cells. Formulations containing metaxalone have been used in the treatment of lower back pain.

NPD-001 is an effective inhibitor of TbrPDEB1. NPD-001 is 10-fold more potent on hPDE4 (hPDE4B1 IC50 = 0.6 nM) than on TbrPDEB1 (IC50 = 4 nM).

Sp-cAMPS triethylamine，一种 cAMP 类似物，是一种依赖 cAMP 的PKAI 和PKAII 的有效激活剂。Sp-cAMPS triethylamine 还是一种有效的竞争性磷酸二酯酶 (PDE3A) 抑制剂，Ki 为 47.6 µM。Sp-cAMPS triethylamine 以EC50为 40 μM 来结合PDE10GAF 域。

8-CPT-Cyclic AMP sodium是一种cAMP依赖性蛋白激酶(PKA)的激活剂和cAMP受体激活剂，也是一种cAMP特异性磷酸二酯酶(PDE VA)的抑制剂（IC50=0.9 μM），对PDE III和PDE IV的IC50分别为24和25μM。

N-Ethyl tadalafil (NEthyl tadalafil) 是一种 CGMP 特异性 3'，5'-环磷酸二酯酶（PDE）抑制剂，可用于研究心绞痛、高血压和肺动脉高压等心血管疾病。

Fraxin (Fraxoside) 是一种白蜡树内酯的糖苷，可从Acer tegmentosum，F. ornus 和A. hippocastanum 等分离得到，具有抗氧化、抗炎和抗转移活性。它能够抑制环腺苷酸磷酸二酯酶，具有抗氧化作用。