CL4F8-6为一种具有电离性的阳离子脂质，其pKa值为6.14。该化合物广泛应用于脂质纳米颗粒(LNP)制备的mRNA疗法中。通过搭载Cas9 mRNA与sgRNA的CL4F8-6 LNP，能有效促进小鼠体内通过CRISPR技术实现的基因敲除。

TCL053是一种可电离脂质，专用于高效导入活性成分（特别是核酸）至细胞。它可与二棕榈酰磷脂酰胆碱(DPPC)、聚乙二醇二肉豆蔻酰基甘油(PEG-DMG)及胆固醇共同构成脂质纳米粒(LNP)，实现Cas9 mRNA与sgRNA向骨骼肌的有效传递。

Dehydroergosterol (DHE) 是一种天然存在的荧光甾醇类似物，是实时探测/阐明生物体中甾醇环境和细胞内甾醇运输的化合物。Dehydroergosterol 是一种胆固醇模拟物，可胆固醇结合蛋白结合，可用于活细胞实时成像。

UK-122 is a potent and selective uPA inhibitor (Ki = 20 nM). The IC(50) of UK122 in a cell-free indirect uPA assay is 0.2 micromol/L. UK122 showed little cytotoxicity against CFPAC-1 cells (IC(50) > 100 micromol/L) but significantly inhibited the migratio

Racecadotril-D5 is intended for use as an internal standard for the quantification of racecadotril by GC- or LC-MS. Racecadotril (T1176) is a prodrug form of the neprilysin (NEP)inhibitor thiorphan. In vivo,racecadotril reduces or prevents castor oil-induced diarrhea without delaying intestinal transit in rats when administered at doses of 80 or 100 mg/kg,respectively. It also decreases the duration of diarrhea and increases body weight gain in a neonatal gnotobiotic pig model of human rotavirus-induced diarrhea. Formulations containing racecadotril have been used in the treatment of acute diarrhea.

(R)-Nepicastat HCl (RS-25560-198 HCl) 是 Nepicastat HCl 的 R-对映异构体，是一种有效的选择性抑制剂，对牛和人多巴胺-β-羟化酶的 IC50 分别为 25.1 nM 和 18.3 nM，对其他 12 种酶和 13 种神经递质受体的亲和力可忽略不计.

Fluvastatinlactone 是 Fluvastatin 的内酯形式，能诱导人类骨骼肌细胞出现肌肉毒性。

Coptisine chloride (NSC-119754) 是从黄连中分离到的一种生物碱，是一种非竞争性 IDO 抑制剂，Ki 值为 5.8 μM，IC50值为 6.3 μM。它是一种 H1N1 神经氨酸酶抑制剂，可用于甲型流感病毒感染，IC50为 104.6 μg/mL。

FR-229934 is a bio-active chemical. Detailed information has not been published.