Bromoenol lactone ((6E)-Bromoenol lactone) 是一种具有的钙依赖性磷脂酶 A2 (iPLA2β) 和丝氨酸蛋白酶抑制剂，可减弱尼古丁诱导的乳腺癌细胞增殖和迁移，抑制电压门控 Ca2+ 和瞬时受体电位经典通道，可抑制角叉菜胶诱导的大鼠后爪前列腺素生成和痛觉过敏。

BMS493 是泛维甲酸受体（RAR）的逆激动剂，可抑制维甲酸诱导的分化，增强核共抑制因子与 RARs 的相互作用，减弱 RA 信号传导，增强了 TPP 诱导的毒性，抑制磷脂酶 A2 活性的增加。

P11 是一种具有选择性的血小板活化因子乙酰水解酶 ( PAFAH1b2 和 PAFAH1b3 ) 抑制剂，阻断 PAFAH1b2 和 PAFAH1b3 介导的底物 PAF 水解为溶血 PAF，可用于研究 PAFAH1b2/3 的细胞功能。

SMS2-IN-1 是一种有效且具有高选择性的鞘磷脂合成酶 2 (SMS2) 抑制剂， IC50 为 6.5 nM，Kd 为 37 nM。SMS2-IN-1 对 SMS2 的选择性比 SMS1 (IC50 为 1000 nM) 多 150 倍。

ML299 (VU0463568) 是一种有效的 DHCR7 抑制剂。 DHCR7 是胆固醇生物合成中的一种酶。 是一种磷脂酶 D1和磷脂酶 D2的选择性变构调节剂和双重抑制剂 (IC50值分别为 6 和 12 nM)，能够抑制 U87-MG 胶质母细胞瘤细胞的侵袭性迁移。

ROC-0929 (compound 13a) is a potent and selective inhibitor of secreted phospholipases A2 (sPLA2s), effectively targeting hGX with an IC50 of 80 nM. It efficiently inhibits the phosphorylation of ERK1/2 and p-38. sPLA2s, belonging to the disulfide-rich, Ca2+-dependent enzyme family, catalyze the hydrolysis of glycero-phospholipids at the sn-2 position, resulting in the release of a fatty acid and a lysophospholipid. ROC-0929 holds promise in researching inflammation-related diseases.

Choline tosylate 是一种能够抑制磷脂酶 A2 和磷脂酶 C 的亲核化合物。通过阻断二酰基甘油 (DAG) 的生成，Choline tosylate 可以抑制小鼠肿瘤的生长。

3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group. It decreases migration and adhesion of B35 neuroblastoma cells and increases cell rounding when used at a concentration of 20 μM. It also inhibits PKC and cytochrome c oxidase activity when used at concentrations of 150 and 50-100 μM, respectively. 3'-sulfo Galactosylsphingosine accumulates in patients with metachromatic leukodystrophy, a lysosomal storage disorder characterized by arylsulfatase A (ASA) deficiency leading to progressive demyelination and neuromotor deficits. In mice lacking ASA, levels of 3'-sulfo galactosylsphingosine increase after one month of age followed by demyelination and neuromotor deficits. 3'-sulfo Galactosylsphingosine has been used as a standard for the quantification of 3'-sulfo galactosylsphingosine by LC-MS.

Ro 23-9358 是一种具抗炎特性的强效分泌型磷脂酶 A2 抑制剂。