DNMDP

目录号：SY-128114

DNMDP是一种高效和选择性的PDE3A抑制剂，具有抗癌活性。DNMDP能与PDE3A结合，促进PDE3A与Schlafen 12(SLFN12)的相互作用。

¥3312.00

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PF-8380 hydrochloride

目录号：SY-128116

PF-8380 hydrochloride 是一种有效的autotaxin 抑制剂，体外酶实验和人类全血细胞实验中，IC50分别为 2.8 nM 和 101 nM。

¥8706.00

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FR-229934

目录号：SY-128118

FR-229934 is a bio-active chemical. Detailed information has not been published.

¥552.00

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OR-1855

目录号：SY-128120

OR-1855 is an active Levosimendan metabolite, has effect on human myometrial contractility.

¥1840.00

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MK-0952

目录号：SY-128122

MK-0952 is a selective PDE4 inhibitor used to treat long-term memory loss and mild cognitive impairment. It is an intrinsically potent inhibitor and has shown limited whole blood activity.

¥6325.00

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PDE7 inhibitor S14

目录号：SY-128124

PDE7 inhibitor S14 is a cell-permeable PDE7 inhibitor that acts by targeting the cyclic adenosine monophosphate (cAMP)/cAMP-response element-binding protein (CREB) pathway.

询价

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NPD-001

目录号：SY-128126

NPD-001 is an effective inhibitor of TbrPDEB1. NPD-001 is 10-fold more potent on hPDE4 (hPDE4B1 IC50 = 0.6 nM) than on TbrPDEB1 (IC50 = 4 nM).

¥1150.00

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endo CNTinh-03

目录号：SY-128128

Endo CNTinh-03 具有抑制作用，可阻止 cAMP 和 cGMP 通过 G 蛋白偶联受体、腺苷酸环化酶及鸟苷酸环化酶的激动剂而升高（IC50为 4 μM）。此外，该化合物能够抑制霍乱毒素与Escherichia coli(STa) 毒素导致的氯离子电流，有效改善小鼠分泌性腹泻的症状，并在多囊肾病模型中防止囊肿的形成。

¥3450.00

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Deltasonamide 2

目录号：SY-128130

Deltasonamide 2 is a competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM.

¥621.00

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