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Milvexian
目录号:SY-126736
Milvexian (BMS-986177) 是一种具有口服生物利用度、小分子、可逆且直接的 凝血因子 XIa (Factor XIa) 拮抗剂。它对人类 FXIa 表现出极高的亲和力 (Ki = 0.11 nM),并对兔、狗、大鼠和小鼠的 FXIa 也具有显著的选择性抑制作用。Milvexian 具有抗凝作用,通过阻断内源性凝血途径的关键环节发挥抗血栓活性,同时在临床前研究中显示出比传统抗凝剂更低的出血风险,常用于血栓形成、卒中预防以及大手术后静脉血栓栓塞的研究。
¥101.00
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Ciraparantag
目录号:SY-126737
Ciraparantag is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoagulants.
¥347.00
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Edoxaban tosylate
目录号:SY-126738
Edoxaban Tosylate (DU-176b tosylate) 是口服具有活力的 factor Xa 选择性抑制剂。它是一种抗凝剂,可用于预防中风,是一种凝血酶和凝血因子 IXaβ (FIXa) 的弱抑制剂,对 FXa 的选择性超过 10000 倍。它具有抗血栓形成的特性,可用于血栓栓塞性疾病的研究。
¥573.00
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Methoxycarbonyl-D-Nle-Gly-Arg-pNA
目录号:SY-126739
Methoxycarbonyl-D-Nle-Gly-Arg-pNA,这是一种底物,主要用于FIXa (Factors IXa) 和 FXa (Factors Xa)的合成蛋白酶。
¥816.00
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BMS-262084
目录号:SY-126740
BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.
¥3553.00
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BMS-654457
目录号:SY-126741
BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).
¥4255.00
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Betrixaban-D6
目录号:SY-126742
Betrixaban-D6 is a deuterium-labeled Betrixaban. Betrixaban (T4341) is a selective and orally efficacious FXa inhibitor.
¥8533.00
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Chloramine-T hydrate
目录号:SY-126743
Chloramine-T serves as a versatile reagent in numerous synthetic procedures, including aminohydroxylation, allylic amination, as a nitrogen source in aziridination reactions of alkenes and olefins, and for the deprotection of thio groups in sulfur-containing molecules. Additionally, it plays a role in the synthesis of Factor Xa inhibitors. At a concentration of 0.2% w/v, Chloramine-T acts as an effective antiseptic agent with bactericidal properties against S. epidermidis, S. aureus, E. faecalis, E. coli, P. mirabilis, and E. cloacae.
¥22195.00
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Pegnivacogin
目录号:SY-126744
Pegnivacogin is a coagulation factor IXa RNA aptamer inhibitor.
¥2990.00
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