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9(S)-HODE cholesteryl ester
目录号:SY-126465
9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation. 9(S)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.
¥7452.00
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Sialyl-Lewis X
目录号:SY-126466
Sialyl-Lewis X (sLeX), a sialylated fucosylated tetrasaccharide and endogenous antigen, serves as a high-affinity ligand for selectins (E-, P-, and L-selectin)[1]. It interacts with ELAM-1 and CD62, consequently inhibiting CD62-mediated neutrophil recruitment to inflammation sites[2].
¥7452.00
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2-Methyldecanenitrile
目录号:SY-126467
2-Methyldecanenitrile, a component in a perfume composition, has an intense peach character with lactonic undertones. It is stable across the whole pH range, allowing the creation of a stable fruity effect at low concentration in any applications, includi
¥2932.00
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3,5-Dibromotyrosine
目录号:SY-126400
3,5-Dibromotyrosine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65914,CAS号为 300-38-9。
¥575.00
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Avenacein Y
目录号:SY-126401
Avenacein Y is a biochemical.
¥1725.00
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(±)11(12)-EpETE
目录号:SY-126402
Eicosapentaenoic acid (EPA) is metabolized into epoxyeicosatetraenoic acids (EpETE) by multiple cytochrome P450 isoforms. The predominant compound of this epoxygenase pathway, (±)17(18)-EpETE, induces relaxation in vascular and airway smooth muscles through its action on large conductance Ca2+-activated K+ (BKCa) channels, specifically by binding to the BKα channel subunits. Another notable epoxygenase pathway derivative, (±)11(12)-EpETE, also generated from EPA via CYP450 activity in both in vitro and in vivo studies, has biological and physiological roles that are yet to be fully elucidated.
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5α-Androstan-3β-ol
目录号:SY-126403
5α-Androstan-3β-ol, a steroidal androgen, demonstrates selective interaction with cellular components, showing affinity for the androgen receptor (AR) with an IC50 of 1.7 µM and activating the pregnane X receptor (PXR) in HepG2 cells with an EC50 of 0.8 µM. It selectively inhibits the hydroxylase activities of 16α- and 6β-hydroxylase over 16β- or 7α-hydroxylase, with IC50 values of 70 and 110 µM, compared to >150 µM for the latter enzymes, indicating a specificity in its enzyme inhibition profile. Additionally, administration of this compound at a dosage of 30 mg/kg results in a decrease in testis weight and sperm production in mice, highlighting its biological effects on male reproductive parameters.
¥575.00
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1-Stearoyl-2-Palmitoyl-3-Oleoyl-rac-glycerol
目录号:SY-126404
1-Stearoyl-2-palmitoyl-3-oleoyl-rac-glycerol is a triacylglycerol comprising stearic acid (at the sn-1 position), palmitic acid (at the sn-2 position), and oleic acid (at the sn-3 position), identified in bovine milk.
¥1725.00
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9-OxoODE
目录号:SY-126405
9-OxoODE, formed through the oxidation of the allylic hydroxyl group in both 9(S)-HODE and 9(R)-HODE, is present in rabbit reticulocyte plasma and mitochondrial membranes as both 9- and 13-oxoODEs, constituting approximately 2% of the total linoleate residues. The majority of these oxidized linoleate residues are esterified to membrane lipids.
¥5175.00
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