PROTAC PTPN2 degrader-2 TFA

目录号：SY-128305

PROTACPTPN2 degrader-2（例187B）TFA 作为PTPN2降解剂，展现出对癌症及代谢性疾病研究的潜在效用。

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YU142670

目录号：SY-128306

YU142670 is a selective inhibitor of OCRL1/INPP5F and OCRL2/INPP5B by targeting OCRL catalytic domain.

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Thienopyridone

目录号：SY-128307

Thienopyridone is a potent and selective inhibitor of phosphatase of regenerating liver (PRL) phosphatase(IC50s of 173 nM, 277 nM and 128 nM for PRL-1, PRL-2, and PRL-3, respectively), and induces p130Cas cleavage and apoptosis and has anticancer effects.

¥1056.00

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cis-Ferulic acid 4-O-β-D-glucopyranoside

目录号：SY-128308

cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7)是一种从西伯利亚白刺分离的酚糖苷，不仅具有抗氧化活性，还能强效抑制磷酸酶PTP1B。

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4-Methylumbelliferyl phosphate disodium

目录号：SY-128309

4-Methylumbelliferyl phosphate disodium (4-MUP) 是一种阴离子有机磷酸酯，作为酸性和碱性磷酸酶（phosphatase）的荧光底物，同时也用作神经毒剂模拟剂。

¥550.00

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3,4-Secocucurbita-4,24-diene-3,26,29-trioic acid

目录号：SY-128310

(24E)-3,4-Seco-cucurbita-4,24-diene-3,26,29-trioic acid can inhibit the activity of protein tyrosine phosphatase 1B (PTP1B), with IC 50 values of 0.4uM.

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NCGC00249987

目录号：SY-128311

NCGC00249987 is a highly selective and allosteric Tyr phosphatase activity of inhibitor of Eya2(Eya2 ED and MBP-Eya2 FL with IC50s of 3 μM and 6.9 μM ).

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PTP1B-IN-4

目录号：SY-128312

PTP1B-IN-4 (NUN-17724)是一种 PTP1B 的变构抑制剂，IC50为8μM。PTP1B-IN-4可用于肥胖症和糖尿病的研究。

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SHP2 protein degrader-2

目录号：SY-128313

SHP2protein degrader-2 (SHP2-D26) 是一种SHP2蛋白PROTAC 降解剂。SHP2protein degrader-2 可降低各种癌细胞中SHP2的表达水平。

¥5005.00

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