MDK-4823

目录号：SY-128314

MDK-4823, also known as LMPTP inhibitor1, is a potent low-molecular-weight tyrosine phosphatase (LMPTP) inhibitor. LMPTP is highly expressed in insulin-target tissues. LMPTP promotes diabetes and insulin resistance in obesity.

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Hexane-1,6-diol

目录号：SY-128315

Hexane-1,6-diol is a diol commonly employed to dissolve liquid-liquid phase separation precipitates. It impairs kinase and phosphatase activity and partially inhibits DNA polymerase.

¥238.00

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SHP2-IN-13

目录号：SY-128316

SHP2-IN-13是一种针对SHP2“tunnel site” 的变构抑制剂，具备高选择性及口服活性，IC50值为83.0 nM。该化合物可作为研究潜力药物，用于治疗携带RTK致癌驱动因素的癌症以及SHP2相关疾病。

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Neocryptotanshinone II

目录号：SY-128317

Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-κB and iNOS signaling pathways.

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Suchilactone

目录号：SY-128318

Suchilactone may have the potential to be developed as a treatment of Alzheimer's Disease.

¥5985.00

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7-Hydroxy-3-(4-hydroxybenzyl)chroman

目录号：SY-128319

7-Hydroxy-3-(4-hydroxybenzyl)chroman shows moderate inhibitory activity against a chymotrypsin-like activity of the proteasome.

¥3249.00

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Icerguastat Carbonate

目录号：SY-128320

Icerguastat (Sephin1) Carbonate，是一种不具有α2-肾上腺素能活性的Guanabenz衍生物，充当磷酸酶调节亚单位PPP1R15A (R15A)的选择性抑制剂。它通过抑制eIF2α去磷酸化来延长保护反应，并表现出抗朊病毒作用。

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Microcystin-LA

目录号：SY-128321

Microcystin LA, a natural toxin, exerts its cytotoxic effects by inhibiting the serine-threonine protein phosphatases PP1 and PP2A with IC50s of 0.3 and 0.3 nM, respectively.

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SHP836

目录号：SY-128322

SHP836 is an inhibitor of SHP2 allosteric (IC50: 12 μM for the full-length SHP2).

¥924.00

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