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Methazolamide-D6
目录号:SY-123519
Methazolamide-D6 is intended for use as an internal standard for the quantification of methazolamide by GC- or LC-MS. Methazolamide (T0106) is a carbonic anhydrase inhibitor. It reduces intraocular pressure and cerebrospinal fluid flow in a rat model of glaucoma. Methazolamide (T0106)reduces electroshock-induced seizures in rats with an ED50 value of 19.2 mg/kg. It also inhibits production of reactive oxygen species (ROS)in a primary cortical neuron (PCN)cellular model of subarachnoid hemorrhage (SAH)and reduces cerebral edema in a mouse model of SAH.3 Methazolamide (T0106) is larvicidal,with a 50% larvicidal concentration (LC50)value of 724 ppm,but has no activity when administered in the diet to adult A. aegypti. Formulations containing methazolamide have been used in the treatment of glaucoma.
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(E)-Dehydrodiconiferyl alcohol
目录号:SY-123520
(E)-Dehydrodiconiferyl alcohol is a potent dual inhibitor of hCA IX and hCA XII, effectively impeding the catalytic activity of both carbonic anhydrase isoforms. Additionally, (E)-Dehydrodiconiferyl alcohol exerts inhibitory effects on the nuclear translocation of NF-κB in the connective tissue of the healing area.
¥8968.00
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4-Amino-6-chlorobenzene-1,3-disulfonamide
目录号:SY-123521
4-Amino-6-chlorobenzene-1,3-disulfonamide 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65709,CAS号为 121-30-2。
¥29.00
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Carbonic anhydrase inhibitor 2
目录号:SY-123522
Carbonic Anhydrase Inhibitor2 (compound 7c) 是一种针对 Carbonic Anhydrase II 抑制剂,有效降低青光眼兔眼压。
¥621.00
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hCAIX-IN-10
目录号:SY-123523
hCAIX-IN-10是一种高效选择性的人碳酸酐酶 IX (hCA IX) 抑制剂 (Ki = 7.1 nM)。它通过干扰缺氧肿瘤微环境中的 pH 调节抑制肿瘤增殖和转移,是抗癌症先导化合物研究的重要工具。
¥1725.00
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cis-1,2-Dihydroxycyclohexane
目录号:SY-123524
cis-1,2-Dihydroxycyclohexane是一种二醇和环己烷衍生物,对carbonic anhydrase具有潜在的抑制作用,可用于生物化学实验和药物合成研究。
¥930.00
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Carbonic anhydrase
目录号:SY-123525
Carbonic anhydrase 是一类含锌金属酶,能高效催化二氧化碳的可逆水合反应。Carbonic anhydrase 可用于癌症、青光眼、肥胖症和癫痫症的研究。
¥912.00
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Sulthiame-D4
目录号:SY-123526
Sulthiame-D4是Sulthiame (T16960)的氘代化合物。
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WES-1
目录号:SY-123527
WES-1(Compound 8g)是一种针对碳酸酐酶IX的抑制剂,其抑制常数(Ki)为55.9 μM。该化合物对包括白血病细胞系(K-562、MOLT-4)、非小细胞肺癌(NCI-H460)、结肠癌(HCT 116、HCT-15)以及黑色素瘤(LOX IMVI)在内的多种癌细胞表现出抗增殖效果。
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