Vitisin A ((+)-Vitisin A) 是一种可从 Vitis vinifera 根中分离出来的白藜芦醇四聚体，具有抗氧化、抗癌、抗细胞凋亡、神经保护和抗炎活性，可改善东莨菪碱诱导的失忆 ICR 小鼠的学习和记忆功能受损，可用于研究退行性疾病。

(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of action of HCA appears to be related to its ability to act as a competitive inhibitor of the enzyme ATP-citrate lyase, which catalyzes the conversion of citrate and coenzyme A to oxaloacetate and acetyl coenzyme A (acetyl-CoA), primary building blocks of fatty acid and cholesterol synthesis.

NSC 295642 是一种磷酸酶抑制剂。NSC 295642 可以显着增加完整细胞中的磷酸Erk 细胞核差异。NSC 295642 可用于癌症研究。

4′-Demethylnobiletin 是一种生物活性代谢物，可以激活PKA/ERK/CREB 信号通路，增强海马神经元中 CRE 介导的转录，并通过刺激ERK 信号逆转与 NMDA 受体拮抗相关的记忆障碍。

CGP78850 is a potent and selective Grb2 SH2-phosphopeptide interaction antagonist that holds potential for cancer research.

Pseudoginsenoside Rh2 has cytotoxicity, it induces mitochondrial apoptosis in A549 cells and is responsible for excessive activation of the Ras/Raf/ERK/p53 pathway. (20Z) -Pseudoginsenoside Rh2 and (20E)-Pseudoginsenoside Rh2 have antioxidative activity.

Tinlorafenib (PF-07284890) (compound 10) 是一种口服具有活力的、具有中枢神经系统 (CNS) 渗透性的 BRAF kinase 抑制剂，能够作用于 BRAFV600E (IC50: 4.25 nM) 和 V600K (IC50: 2.7 nM)。Tinlorafenib 能够用于 BRAF 相关的中枢神经系统恶性和良性肿瘤以及颅外恶性肿瘤的研究。

PF-07284892(ARRY-558)是一种具有口服活性的变构SHP2抑制剂(IC50=21 nM)，能够降低pERK的表达，可用于研究实体瘤。

7alpha,15-Dihydroxydehydroabietic acid may exhibit significant cytotoxic activity.