PROTAC FLT-3 degrader 1

目录号：SY-120877

PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD) with an IC50 of 0.6 nM and exhibits anti-proliferative activity.

¥6006.00

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Eucannabinolide

目录号：SY-120878

Eucannabinolide exhibits in vivo antileukemic activity.

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PM-81I

目录号：SY-120879

PM-81I为一种高效STAT6抑制剂（针对SH2结构域），可显著减少STAT6的磷酸化水平。适用于研究过敏性肺病、过敏性鼻炎、慢性阻塞性肺病或癌症。

¥4312.00

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HJC0149

目录号：SY-120880

HJC0149 is a potent orally bioavailable signal transducer and activator of transcription 3 inhibitor.

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Antitumor agent-73

目录号：SY-120881

Antitumor agent-73是一种Diosgenin衍生物，具有阻断STAT3信号传导和外源性激活Pdia3/ERp57的能力。该化合物对多种癌细胞表现出显著的抗肿瘤活性，其效力为Diosgenin的7.9至341.7倍。

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LLL3

目录号：SY-120882

LLL3 is a small molecule STAT3 inhibitor.

¥1690.00

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Ascochlorin

目录号：SY-120883

Ascochlorin (Ilicicolin D), an isoprenoid antibiotic, primarily exerts its anti-tumor properties by inhibiting the STAT3 signaling pathway. It induces apoptosis and possesses anti-inflammatory activity[1][2][3].

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8-Epixanthatin

目录号：SY-120884

8-Epixanthatin, a light-induced growth inhibitor, mediates the phototropic curvature in sunflower (Helianthus annuus) hypocotyls, it can induce germination of O. cumana at nano- to micromolar concentrations. 8-Epixanthatin has antiprotozoal activity.

¥1540.00

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3-(2-Hydroxyphenyl)-2-propenal

目录号：SY-120885

3-(2-Hydroxyphenyl)-2-propenal 是一种从肉桂（Cinnamomum cassia）茎皮中分离的苯丙烷类天然醛。3-(2-Hydroxyphenyl)-2-propenal 通过直接结合 STAT3 并抑制其 Tyr705 位点磷酸化及核转位，同时通过抑制 Wnt/β-catenin 信号通路调控下游靶基因表达，从而抑制多种肿瘤细胞增殖并诱导凋亡。(E)-2-Hydroxycinnamaldehyde 具有抗肿瘤活性，可用于肿瘤研究。

¥1288.00

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