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Mast cell degranulating peptide (28-49)
目录号:SY-123419
Mast cell degranulating peptide (28-49) is a bee venom depolarizer that enhances cGMP levels in cerebellum tablets of mice.
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YM 244769 hydrochloride
目录号:SY-123387
inhibitor of the reverse mode of Na+/Ca2+ exchange (NCX)
¥1232.00
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(-)-Praeruptorin A
目录号:SY-123321
(-)-Praeruptorin A has anti-inflammatory, anti-contractile and anti-hyperplasia activities, it exerts distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis;it also can significantly suppress airway inflammation and airway remodeling induced by ovalbumin challenge, and is a potential candidate for the treatment of asthma. (-)-Praeruptorin A resensitizes Pgp-mediated MDR (Pgp-MDR) cancer cells to cancer drugs.
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Praziquantel
目录号:SY-123211
Praziquantel (Droncit) 是一种外消旋混合物,由 (R)-Praziquantel 和 (S)-Praziquantel 组成。它可研究血吸虫病。
¥88.00
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D-myo-Inositol-1,2-diphosphate (sodium salt)
目录号:SY-123309
Ins(1,2)P2 (sodium salt) is one of the many inositol phosphate (InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals. The most studied InsP Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,2)P2 (tested as the D/L racemic mixture) is ~1,000-fold less potent than Ins(1,4,5)P3 at initiating Ca2+ release when injected into Xenopus oocytes.
¥6106.00
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Fargesone B
目录号:SY-123351
Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium influxes in a nonselective manner.
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Leconotide
目录号:SY-123431
Leconotide is a calcium channel blocker and antihyperalgesia agent; isolated from the venom of the cone snail, Conus catus.
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2',3'-Cyclic NADP disodium
目录号:SY-123381
2',3'-Cyclic NADP disodium (2',3'-cNADP+; β-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate) 是 2',3'-环状核苷酸 3'-磷酸二酯酶 (CNP) 的一种底物,CNP 在髓鞘中丰富存在。此化合物被用于偶联酶测定以量化 CNP 活性。使用 2',3'-Cyclic NADP disodium (5 μM) 可以增加钙超载引发的钙释放并防止大鼠脑线粒体发生钙诱导的肿胀。
¥1943.00
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N106
目录号:SY-123215
N106 是 SUMO 激活酶 E1 连接酶的激活剂,并触发 SERCA2a 的内在 sumoylation。 N106 可用于有关心力衰竭的研究。
¥429.00
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