TRV120055, a Gq-biased agonist, demonstrates a 10-fold higher molecular efficacy when tested against the AT1R-Gq fusion protein in comparison to the AT1R-βarr2 fusion protein.

TRV056 is a Gq-biased agonist of the angiotensin II type 1 receptor (AT1R), demonstrating efficacy in stimulating Gq-mediated cellular signaling. It can serve as a foundation for the development of Gq-biased AT1R agonists.

PF-4455242 HCl是一种选择性和可口服的κ-opioid receptor拮抗剂，可促进脉动性黄体生成素(LH)分泌和卵巢活动，具有抗抑郁作用。

Acetyl tetrapeptide-15 targets neuro sensitive skin which by decreasing the release of pro-inflammatory mediators.

Endomorphin 2 TFA, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM. a high affinity, highly selective agonist of the μ-opioid receptor,

[Sar1, Ile8]-Angiotensin II 是一种在血管平滑肌细胞中有多种作用（如正常动脉的收缩，培养的细胞或病变血管的肥大或增生等）的多肽，。

Chymase 是一种蛋白质消化酶，主要定位于肥大细胞 (MC)、成纤维细胞和血管内皮细胞。在炎症信号、组织损伤和细胞应激的情况下，Chymase 会释放到胞外间质中。它还参与血管紧张素 II (Ang II) 的生成，是心血管疾病研究的关键成分。

SNC 162 是一种高效和选择性的delta-opioid receptor（DOR，δ-opioid）激动剂，IC50 值为 0.94 nM，具有镇痛、抗抑郁和抗心律失常的效果.

Porcine dynorphin A (1-13) is a potent, endogenous κ-opioid receptor agonist that exhibits antinociceptive effects at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons, similar to increases observed with acute exposure to other agents.