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PKC-theta inhibitor
目录号:SY-109957
PKC-theta inhibitor 是一种PKC-θ抑制剂,IC50值为 12 nM。
¥561.00
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MORF-627
目录号:SY-109763
MORF-627是一种口服有效的整合素αvβ6 (integrin αvβ6) 选择性抑制剂,在人血清配体结合试验中的IC50为9.2 nM。它能抑制αvβ6介导的TGF-β1激活,IC50为2.63 nM,并且能抑制SMAD2/3磷酸化,IC50为8.3 nM。MORF-627对Bleomycin诱发的小鼠肺纤维化具有改善作用。
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EGCG Octaacetate
目录号:SY-109205
EGCG Octaacetate 是表没食子儿茶素没食子酸酯的前药,对革兰氏阳性菌和革兰氏阴性菌有潜在抗菌可能。它可下调 PI3K/Akt/NFκB 磷酸化和 p65 乙酰化来降低促炎介质水平,减少小鼠结肠炎引起的结肠癌。
¥1615.00
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Fibronectin Active Fragment Control
目录号:SY-109796
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins.In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin
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Recilisib sodium
目录号:SY-109272
Recilisib, also known as ON 01210.Na, is a radioprotectant, which modifys cell cycle distribution patterns in cancer cells subjected to radiation therapy, and it has been identified as a potential candidate for radiation protection studies. It appears tha
¥428.00
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Bexotegrast
目录号:SY-109702
Bexotegrast (PLN-74809)是一种具有口服活性和强效性的 αvβ6和αvβ1 整合素抑制剂,具有抗纤维化作用,抑制 αvβ6 和 αvβ1 诱导的 TGF-β 激活,可用于研究特发性肺纤维化(IPF)和非特异性间质性肺炎(NSIP)。
¥924.00
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