Fomepizole hydrochloride（4-Methylpyrazole）是一种高效、具口服活性的细胞色素P450（CYP2E1）和竞争性乙醇脱氢酶（alcohol dehydrogenase）抑制剂，阻止甲醇和乙二醇转化为有毒代谢产物，具有用于乙二醇或甲醇中毒解毒的潜力。

ML252是一种钾离子通道(potassium channel)的选择性抑制剂，主要针对KCNQ2 (Kv7.2，IC50=69 nM)。同时，ML252对细胞色素Cytochrome P450也有抑制作用，其IC50值分别为CYP1A2为6.1 nM、CYP2C9为18.9 nM、CYP3A4为3.9 nM、CYP2D6为19.9 nM。

22-HDHA is an oxidation product of docosahexaenoic acid . In vitro, it is formed upon incubation of rat liver microsomes with DHA and NADPH and also by the human cytochrome P450 (CYP) isoform CYP4F3B in BTI-TN-5B1-4 microsomes. Serum levels of 22-HDHA increase following dietary DHA supplementation in humans.

(R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM).

Senkirkin is a pyrrolizidine alkaloid with hepatotoxicity.

Dibenzylfluorescein（DBF）是一款荧光探针，作为细胞色素P450（CYP）亚型，包括CYP3A4、CYP2C8、CYP2C9、CYP2C19和CYP19的特异性底物，常在Km值0.87-1.9 µM（Ex=485nm，Em=535nm）范围内应用。该探针主要用于监测药物或疾病导致的CYP催化活性变化。