HM03 trihydrochloride

目录号：SY-109630

HM03 trihydrochloride is a potent and selective inhibitor of HSPA5, also known as Bip or Grp78. It exhibits anticancer activity.

¥345.00

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MAO A/HSP90-IN-1

目录号：SY-109631

MAO A/HSP90-IN-1 (4-b) 是一种针对MAO A和HSP90的双重抑制剂，展现在恶性胶质瘤GL26细胞上的IC50为1.77 μM，针对HSP90α的IC50为0.019 μM。该化合物能够通过抑制MAO A活性和HSP90结合，以及降低HER2和phospho-Akt表达，进而抗击恶性胶质瘤（GMB）。同时，MAO A/HSP90-IN-1 (4-b)可减少PD-L1的表达，从而降低T细胞活化的抑制，有望用来抑制肿瘤的免疫逃逸。该化合物适用于脑肿瘤相关疾病研究。

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Hsp70-derived octapeptide

目录号：SY-109632

A group of tetratricopeptide repeat (TPR)-containing proteins has been shown to interact with the C-terminal domain of the 70 kDa heat-shock cognate protein (hsc70). In the present study, the effect of the TPR-containing proteins, including the C-terminus

¥690.00

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SW02

目录号：SY-109633

SW02 是一种有效的 Hsp70 的 ATPase 活性激活剂 (EC50: 150 μM)。SW02 能够积累总 tau 和磷酸化 tau (pTau)。

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DiaPep277

目录号：SY-109634

DiaPep277为源自HSP60第437-460位点的24个氨基酸组成的多肽，能够抑制NOD小鼠β-细胞破坏进展，并在糖尿病动物模型中对T细胞表现出免疫调节功能。

¥862.00

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Bimoclomol

目录号：SY-109635

Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.

¥2058.00

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