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MS21
目录号:SY-109296
MS21 is a unique AKT degrader that selectively hampers the proliferation of cancers with mutations in the PI3K/PTEN pathway, alongside wild-type KRAS and BRAF.
¥3465.00
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2',3'-Dehydrosalannol
目录号:SY-109297
2',3'-Dehydrosalannol possesses antifeedant activity against Spodptera litura. It shows anticancer effects on triple-negative breast cancer(TNBC), it inhibits cathepsin-mediated pro-survival signaling which resulted in growth arrest of TNBC cells.
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Carpaine
目录号:SY-109298
Carpaine是一种具有抗疟活性的天然产物,在NL20 cell中对P. falciparum的IC50约为4μM。Carpaine具有心脏保护和抗炎作用,能够激活FAK、ERK1/2和AKT通路,抑制ROS产生。
¥3848.00
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MS5033
目录号:SY-109299
MS5033 是一种有效的基于 PROTAC 的 AKT 降解剂,在 PC3 细胞中的 DC50值为 430 nM。
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Isopropyl ferulate
目录号:SY-109300
Isopropyl ferulate 来源于羌活(Rhizoma et Radix Notopterygii)的活性物质,对 PANC-1 胰腺癌细胞具有显著细胞毒性,其 PC50 为 17.5 μg/mL。网络药理学分析提示其可调控 PI3K/Akt/mTOR、ErbB 与 IL-17 等信号通路,并在 IMQ 诱导及 LPS 刺激模型中获得验证,证明 Isopropyl ferulate 在癌症治疗研究中的重要意义。
¥172.00
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Nyasol
目录号:SY-109301
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antifungal activity, it is significantly
¥5985.00
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