Eudebeiolide B，一种自荔枝草分离得的化合物，能通过调控RANKL诱导的NF-κB、c-Fos及钙信号来抑制破骨细胞的生成，适用于研究与破骨细胞相关的疾病。

Insulinglargine 是一种长效胰岛素类似物。Insulinglargine 可用于研究糖尿病。

SPA0355 是硫脲衍生物，展现抗氧化和抗炎特性。它抑制RANKL(核因子 κB 受体活化因子配体)在初级骨髓来源巨噬细胞中的诱导破骨细胞生成，影响MAPKs、Akt和NF-κB通路的激活。同时，SPA0355 促成成骨细胞分化，提高碱性磷酸酶活性和矿化结节形成。通过刺激成骨细胞分化并抑制破骨细胞吸收，SPA0355 可以保护去卵巢小鼠免受骨丢失，适用于绝经后骨质疏松症的研究。

(+)-Matairesinol exhibits immunomodulatory activity; it also shows inhibition of the discoloration of yellowtail dark muscle.

CMX-2043 is a drug potentially to block oxidative damage and activate cell survival pathways.

Gambogic amide acts as a potent and selective agonist for TrkA, promoting tyrosine phosphorylation and activating downstream signaling pathways such as Akt and MAPK. It specifically binds to the cytoplasmic juxtamembrane domain of the TrkA receptor, stimulating dimerization and activation. The compound demonstrates neuroprotective properties by preventing neuronal cell death caused by glutamate. Additionally, gambogic amide shows enhanced efficacy in a transient middle cerebral artery occlusion model of stroke and may be useful for investigating neurodegenerative diseases and stroke [1].