PTPN2/1-IN-2

目录号：SY-128346

PTPN2/1-IN-2，作为一种PTPN2/1拮抗剂，广泛应用于多种肿瘤的研究领域。

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DIPQUO

目录号：SY-128296

DIPQUO is an activator of bone marker alkaline phosphatase (ALP). DIPQUO promotes the differentiation of mouse and human osteoblasts by activating p38MAPK-β. The EC50 in C2C12 cells was 6.27 μM.

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Tagitinin A

目录号：SY-128178

Tagitinin A （肿柄菊内酯 A）是一种天然的倍半萜内酯化合物，作为过氧化物酶体增殖物激活受体α/γ（PPARα/PPARγ)的双重激动剂，在糖尿病研究中发挥抗高血糖和抗高血脂作用。Tagitinin A 能够直接结合PPARγ配体结合域（IC50=55 μM），也能刺激PPARα依赖性SULT2A1基因启动子的转录激活。作为植物毒素时Tagitinin A对小麦胚芽鞘的生长有显著的抑制作用。

¥9832.00

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Tirotundin

目录号：SY-128182

Tirotundin is a PPARα/γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activation of NF-kappa B, thereby, the synthesis of inflammatory mediators such as cytokines and chemo

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Momordicoside A

目录号：SY-128270

Momordicoside A（苦瓜苷A）是从苦瓜（Momordica charantia L.）中分离得到的三萜皂苷类化合物，具有多种生物活性，对蛋白酪氨酸磷酸酶（PTP1B）具有抑制作用，可用于治疗2型糖尿病。此外，Momordicoside A还具有抗炎、抗氧化、抗肿瘤、抗HIV/AIDS的潜在作用。

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PROTAC PTPN2 degrader-2 TFA

目录号：SY-128305

PROTACPTPN2 degrader-2（例187B）TFA 作为PTPN2降解剂，展现出对癌症及代谢性疾病研究的潜在效用。

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Thienopyridone

目录号：SY-128307

Thienopyridone is a potent and selective inhibitor of phosphatase of regenerating liver (PRL) phosphatase(IC50s of 173 nM, 277 nM and 128 nM for PRL-1, PRL-2, and PRL-3, respectively), and induces p130Cas cleavage and apoptosis and has anticancer effects.

¥1056.00

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MSI-1436 lactate

目录号：SY-128279

MSI-1436 lactate is a selective, non-competitive the enzyme protein-tyrosine phosphatase 1B (PTB1B)inhibitor(IC50 of appr 1 μM)

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Isotanshinone IIA

目录号：SY-128336

Isotanshinone IIA, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM. is an abietane-type diterpene metabolite.

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