Tirotundin

目录号：SY-128182

Tirotundin is a PPARα/γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activation of NF-kappa B, thereby, the synthesis of inflammatory mediators such as cytokines and chemo

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7-Hydroxy-3-(4-hydroxybenzyl)chroman

目录号：SY-128319

7-Hydroxy-3-(4-hydroxybenzyl)chroman shows moderate inhibitory activity against a chymotrypsin-like activity of the proteasome.

¥3249.00

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A12B4C3

目录号：SY-128340

A12B4C3 is a selective inhibitor of hPNKP phosphatase.

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PROTAC PTPN2 degrader-1

目录号：SY-128331

PROTACPTPN2 degrader-1 (compound example 77) 是一种有效的 PTPN2降解剂。PROTACPTPN2 degrader-1 具有研究癌症或代谢性疾病的潜力。

¥6930.00

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DSHN

目录号：SY-128333

DSHN is a small heterodimer partner (SHP) activator. DSHN transcriptionally activates SHP mRNA, and stabilizes the SHP protein by preventing its ubiquitination and degradation.

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SHP836

目录号：SY-128322

SHP836 is an inhibitor of SHP2 allosteric (IC50: 12 μM for the full-length SHP2).

¥924.00

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Aloe-emodin-8-O-β-D-glucopyranoside

目录号：SY-128207

Aloe-emodin-8-O-β-D-glucopyranoside (Aloe-emodin-8-O-beta-D-glucopyranoside) 是一种分离自Saussrurea lappa 中的化合物，是一种温和的人类蛋白酪氨酸磷酸酶 1B 抑制剂，其IC50=26.6 μM。

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BCI hydrochloride

目录号：SY-128222

BCI hydrochloride ((E)-BCI hydrochloride) 是一种选择性双特异性磷酸酶 6 （DUSP6） 抑制剂，抑制 RANKL 介导的破骨细胞生成并减轻卵巢切除术诱导的骨质流失。BCI hydrochloride 具有抗炎活性，可减少活性氧 (ROS) 的产生，部分逆转 AE 诱导的细胞毒性，增加 ERK 的活性，可用于研究炎症性疾病。

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NCGC00249987

目录号：SY-128311

NCGC00249987 is a highly selective and allosteric Tyr phosphatase activity of inhibitor of Eya2(Eya2 ED and MBP-Eya2 FL with IC50s of 3 μM and 6.9 μM ).

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