GPR35 agonist 1 is a highly effective and specific GPR35/CXCR8 agonist (EC50: 5.8 nM).

Commendamide is a natural bacterial product that was discovered in a screen for commensal bacteria effector genes (Cbegs). Cbeg12 is a bacterial effector gene that encodes for its production. Commendamide is structurally similar to long-chain N-acyl-amides, which commonly signal, in mammals, through G protein-coupled receptors. Commendamide activates GPR132 (also known as G2A) with an EC50 value of 11.8 μM.

ATC0065 dihydrochloride is a novel nonpeptidic and potent melanin-concentrating hormone receptor 1 (MCHR1) selective antagonist.

Melanin Concentrating Hormone (MCH), a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus.

Monomethyl fumarate D3 is a deuterium labeled Monomethyl fumarate.

Miricorilant (CORT 118335) 是一种选择性糖皮质激素受体调节剂，可用于研究消化系统疾病和代谢疾病。

AZ12216052 是一种 GRP8 拮抗剂，具有抗焦虑和抗炎活性，可用于研究肥胖和代谢紊乱。

LP-471756 是 GPR139 的特异性拮抗剂，可抑制 LP-360924 刺激的 cAMP 产生 (IC50 = 640 nM)。

SCO-267是一种GPR40/FFAR1完全激动剂，EC50=12 nM，有效刺激糖尿病大鼠胰岛素分泌和GLP-1释放，改善糖耐量，可用于治疗2型糖尿病。