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Isolimonexic acid
目录号:SY-123770
Isolimonexic acid exhibits cytotoxicity on MCF-7 cell lines, it also inhibits Panc-28 cancer cell growth.
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Neoquassin
目录号:SY-123771
Quassin, neoquassin and picrasinoside B are insecticide quassinoids.
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Methysticin
目录号:SY-123772
Methysticin, a major kavalactone extracted from kava, can induce CYP1A1.
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Dihydrosesamin
目录号:SY-123773
Dihydrosesamin是一种天然产物,属于柏科扁柏属,其产品编号为 TN3865,CAS号为 83708-70-7。Dihydrosesamin可用作对照参考。
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N-Nornuciferine
目录号:SY-123774
N-Nornuciferine 是存在于莲叶中的阿朴啡类生物碱,能够强效抑制 CYP2D6,其 IC50 为 3.76 μM、Ki 为 2.34 μM。药动学研究表明其可迅速吸收入血,在给药 0.9 h 与 1.65 h 分别达到 Cmax 1.71 μg/mL 与 0.57 μg/mL。静脉给药(10 mg/kg)后分布容积为 9.48–15.17 L/kg,消除半衰期为 2.09–3.84 h;口服生物利用度为 58.13–79.91%。在 20 mg/kg 静脉给药下,其可快速穿越血脑屏障,于 0.89–1.22 h 达到游离 Cmax 值 0.32 μg/mL 与 0.16 μg/mL。
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Kushenol K
目录号:SY-123775
Kushenol K is a potent and Selective Inhibitor of cGMP Phosphodiesterase 5, it also has inhibitory effects on diacylglycerol acyltransferase (DGAT). Kushenol K shows weak antiviral activity against Herpes simplex virus types I and II.
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