Fadrozole is a selective inhibitor of aromatase. It also effective in the treatment of estrogen-dependent diseases including breast cancer.

Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 17-HETE is a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. 17(R)-HETE is an inactive isomer of 17-HETE, whereas the (S) enantiomer can inhibit proximal tubule ATPase activity at a concentration of 2 μM.

CYP2E1-IN-1 (Compound 10) 是一种口服有效的细胞色素 P450 2E1 (CYP2E1) 抑制剂，具有Kd为 7.02 μM，IC50为 1.64 μM，Ki为 0.897 μM的特性。该化合物通过激活Nrf2/HO-1信号通路来降低ROS的产生，从而缓解胰腺损伤。CYP2E1-IN-1 具备显著的抗炎和抗氧化活性，能够有效减轻严重急性胰腺炎 (SAP) 的炎症及氧化应激，并可用于SAP及其他炎症相关疾病的研究。

Peucedanol acts as a non-competitive inhibitor of CYP3A4 with a K i value of 4.07 μM, while serving as a competitive inhibitor for CYP1A2 and CYP2D6 with K i values of 3.39 μM and 6.77 μM, respectively [1].

Seviteronel racemate is the racemate form of Seviteronel and is a potent inhibitor of CYP17 lyase.

15-Hydroxydehydroabietic acid exhibits a promising alpha-glucosidase inhibitory activity, it also shows significant antibacterial activities.