OSI-413 (free base) (CP 373413) 是Erlotinib的主要代谢产物。Erlotinib (CP-358774) 是一种直接作用于EGFR的酪氨酸激酶抑制剂，对人EGFR的 IC50为 2 nM。

Rivaroxabandiol是Rivaroxaban的代谢产物。Rivaroxaban是一种高效且选择性的凝血因子Xa (FXa) 直接抑制剂，其IC50为0.7 nM，Ki为0.4 nM。

PD 109488 is a metabolite of quinapril and is a derivative of Quinapril that acts as an ACE inhibitor. Inhibition of ACE prevents the conversion of signaling peptide angiotensin I into angiotensin II, which acts as a potent vasoconstrictor. Reduced levels of angiotensin II also reduces the amount of aldosterone that is expressed due to RAAS signaling.

(9E)-Erythromycin A oxime is a metabolite of the semisynthetic antibiotic roxithromycin .

Clocortolone pivalate是一种合成糖皮质激素和皮质类固醇酯，适用于治疗脂溢性皮炎、接触性皮炎、特应性皮炎及银屑病。

N-Desethyl Bimatoprost (17-phenyl trinor PGF2α amide) is an F-series PG analog in which the C-1 carboxyl group has been modified to an unsubstituted amide. PG esters have been shown to have ocular hypotensive activity. PG N-ethyl amides were recently introduced as alternative PG hypotensive prodrugs. Although it has been claimed that PG amides are not converted to the free acids in vivo, studies have shown that bovine and human corneal tissue converts the amides of various PGs to the free acids with a conversion efficiency of about 10-20% relative to the hydrolysis of isopropyl esters. 17-phenyl trinor PGF2α amide would be expected to show the typical intraocular effects of latanoprost, but with the much slower hydrolysis pharmacokinetics of the PG N-amides.