4-(3,4-Dimethoxyphenyl)-3-buten-1-ol

目录号：SY-121037

(E)-4-(3,4-dimethoxyphenyl)but-3-en-1-ol may promote melanin synthesis via USF1 dependent fashion and could be used as a clinical therapeutic agent against hypopigmentation-associated diseases.

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Ravoxertinib hydrochloride

目录号：SY-121039

Ravoxertinib hydrochloride is an orally bioavailable and selective inhibitor for ERK kinase activity (IC50: 6.1 nM and 3.1 nM for ERK1 and ERK2, respectively).

¥770.00

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Ganoderic acid X

目录号：SY-121040

Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). It is a potential anticancer drug, inhibits topoisomerases and induces apoptosis of cancer cells.

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6'-Sialyllactose

目录号：SY-121041

6'-Sialyllactose (6'-SL) 是人乳中含量最丰富的低聚糖之一，具有显著的益生元活性，能促进有益菌(如双歧杆菌和乳杆菌)生长，同时抑制有害菌增殖。此外，6'-SL 展现出多效生物活性：它能通过调节肠道菌群与脑-肠轴缓解焦虑；通过抑制 VEGF 介导的血管生成(抑制 Akt-ERK 信号)缓解前列腺增生；并能增加肌肉质量与力量以提升运动耐力。此外，它还能减少铜绿假单胞菌在肺细胞中的内化。

¥462.00

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MEK-IN-6

目录号：SY-121042

MEK-IN-6（Example 69）是一种针对MEK的抑制剂，在A375细胞中有效抑制ERK1/2（THR202/Tyr204）的磷酸化，其IC50值为2 nM。此化合物主要应用于癌症研究领域。

¥1463.00

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2-Hydroxy-3-methylanthraquinone

目录号：SY-121043

2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 activation mediated apoptotic induction.

¥4174.00

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