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3-Oxo-7-hydroxychol-4-enoic acid
目录号:SY-126425
3-Oxo-7-hydroxychol-4-enoic acid 是一种内源性代谢产物,可能作为肝胆疾病预后不良的重要指标。
¥6210.00
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10-Nitrooleic acid
目录号:SY-126417
10-Nitrooleic acid(CXA-10)是一种硝化不饱和脂肪酸和内源性信号分子,在氧化应激、炎症、代谢等多方面具有作用。
¥943.00
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Evernic acid
目录号:SY-126414
Evernic acid是一种发现于Evernia prunastri的天然代谢物,能够穿透血脑屏障,能够抑制TrxR1酶活性和NF-κB通路,在帕金森病模型中具有神经保护和抗炎作用,还具有抗癌、抗真菌和抗菌作用。
¥943.00
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ent-8-iso-15(S)-Prostaglandin F2α
目录号:SY-126434
Isoprostanes are produced by the non-enzymatic, free radical peroxidation of phospholipid-esterified arachidonic acid. They have been used as biomarkers of oxidative stress, but they also have been found to have potent biological activity. ent-8-iso-15(S)-Prostaglandin F2α (ent-8-iso-15(S)-PGF2α) is a potent vasoconstrictor of porcine retinal and brain microvessels with EC50 values of 15 and 24 nM, respectively. This isoprostane is about ten-fold more potent than 8-iso-PGF2α in a whole blood platelet aggregation inhibition assay.
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(-)-Jasmonoyl-L-isoleucine
目录号:SY-126443
(-)-Jasmonoyl-L-isoleucine ((-)-JA-L-Ile),为(+)-JA-L-Ile的对映体,是一种无活性的内源性激素。
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Lentztrehalose A
目录号:SY-126421
Lentztrehalose A, a disaccharide microbial metabolite identified in Lentzea, exhibits a range of biological activities. This compound specifically inhibits M. smegmatis trehalase—an enzyme involved in trehalose metabolism—more effectively than trehalase from porcine kidney, with IC50 values of 0.67 mM and >20 mM, respectively. Additionally, Lentztrehalose A at a concentration of 100 mM promotes autophagy in MeWo melanoma and OVK18 ovarian cancer cells. When administered at 50 mg/kg daily, it enhances survival rates and impedes tumor growth in a Sarcoma 180 murine sarcoma model.
¥6773.00
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(±)-γ-Tocopherol
目录号:SY-126430
(±)-γ-Tocopherol是一种内源性代谢物和维生素E的一种形式,具有抗氧化和抗炎特性,能减少LPS和IL-1β诱导的前列腺素(PGE2)的合成。
¥206.00
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Calcium 2-oxoglutarate
目录号:SY-126442
Calcium 2-oxoglutarate is an intermediate in the production of GTP or ATP in the Krebs cycle. It is a reversible inhibitor of tyrosinase (IC50: 15 mM).
¥99.00
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2-Myristyldipalmitin
目录号:SY-126424
2-Myristyldipalmitin (PMP) 是一种棕榈酸甘油三酯,具有成为威尔逊氏病 (WD) 脂质标记物的潜力。
¥3622.00
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