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Anthraflavic acid
目录号:SY-123653
Anthraflavic acid (2,6-Dihydroxyanthraquinone) 是一种特异性细胞色素 P-448抑制剂,细胞色素 P-448 是与许多化学致癌物质的激活密切相关的酶系统。它是一种类黄酮,有效的IQ 诱变性抑制剂,能够抑制微粒体和胞质激活途径。
¥22.00
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L-Ascorbic Acid-13C6
目录号:SY-123378
L-Ascorbic Acid-13C6是L-Ascorbic Acid (T0928)的 13C 的标记化合物。L-Ascorbic Acid的CAS号为50-81-7。L-Ascorbic acid是一种电子供体,是一种内源性抗氧化剂。它选择性抑制 Cav3.2 通道,IC50为 6.5 μM。它还是一种胶原沉积促进剂和弹性生成抑制剂,可对抗细菌感染、解毒反应和胶原蛋白的形成。
¥2426.00
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(S)-Lercanidipine-D3 hydrochloride
目录号:SY-123372
(S)-Lercanidipine-D3 hydrochloride is a deuterium labeled Lercanidipine D3 hydrochloride. (S)-Lercanidipine hydrochloride (T12804) is an agent of antihypertensive.
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(S)-Amlodipine-D4
目录号:SY-123376
(S)-Amlodipine-D4是(S)-Amlodipine (T1545)的氘代化合物。 (S)-Amlodipine的CAS号为103129-82-4。Levamlodipine是一种二氢吡啶钙通道阻滞剂,具有舒张血管的作用,可用于高血压和心绞痛的研究。
¥5336.00
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Isotachysterol 3
目录号:SY-123382
Isotachysterol 3 是一种活性维生素 D 结构类似物的开环甾体化合物,也是制备维生素 D₃ 过程中的一种杂质。Isotachysterol 3 在无肾大鼠模型中能够显著刺激肠道钙的转运和骨钙动员。Isotachysterol 3 可用于不依赖于肾脏 1α-羟化的维生素 D 代谢研究。
¥2415.00
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Marmin
目录号:SY-123370
Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the prevention of the effects of endogenous acetylcholine and histamine.
¥2755.00
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Acetylcholine-D16 bromide
目录号:SY-123374
Acetylcholine-D16 bromide是Acetylcholine bromide (T20344)中氘置换的一种形式。
¥2530.00
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Lyso-Globotriaosylceramide (d18:1)
目录号:SY-123384
Lyso-globotriaosylceramide is a form of globotriaosylceramide that is lacking the fatty acyl group. It binds to Shiga toxin 1 (Stx1) in the presence of cholesterol and phosphatidylcholine but does not bind Stx2. It also reduces viability and aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate when used at concentrations of 50 and 1 μM, respectively. Lyso-globotriaosylceramide accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. It also accumulates in the urine, kidney, and plasma of patients with Fabry disease. Lyso-globotriaosylceramide levels decrease in response to administration of the α-galactosidase inhibitor 1-deoxygalactonojirimycin in a transgenic mouse model of Fabry disease. Decreases in plasma and urine concentrations of lyso-globotriaosylceramide have been used as a biomarker for efficacy of enzyme replacement th
¥11550.00
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Fukinolic acid
目录号:SY-123368
Fukinolic acid 是一种苄基酒石酸酯,作为血管扩张剂,显示出抑制肠道病毒A71 (EV-A71) 复制的效果。它是受体调控的Ca2+通道 (ROC) 的抑制剂,通过抑制 Norepinephrine 激活的 ROC 来阻止细胞外Ca2+ 的内流,而不影响电压依赖性Ca2+通道。
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