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8-Bromo-cGMP sodium
目录号:SY-123147
8-Bromo-cGMP sodium 是一种 PKG 激活剂, 是 cGMP 的膜渗透性类似物。8-Bromo-cGMP sodium 具有缓解疼痛和血管舒张作用,可显着抑制 Ca2+ 宏观电流,抑制高 K+ 刺激的胰岛素释放。
¥539.00
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L-Phenylalanine-D7
目录号:SY-123404
L-Phenylalanine-D7是L-Phenylalanine (T3377)的氘代物。L-Phenylalanine ( (S)-2-Amino-3-phenylpropionic acid)是从大肠杆菌分离的必需氨基酸,作为电压依赖性α2δ亚基Ca2+通道的拮抗剂,具有Ki值为980 nM。此外,它是NMDARs (KB573 μM)和非NMDARs的甘氨酸和谷氨酸结合位点的竞争性拮抗剂。L-Phenylalanine 被广泛用于食品香料和药品的生产。
¥5175.00
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Marmin
目录号:SY-123370
Marmin have anti-ulcer effects, which are ascribed primarily to the maintenance of the mucosal barrier integrity and inhibition of gastric motor activity and secondarily due to the prevention of the effects of endogenous acetylcholine and histamine.
¥2755.00
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TMB 8 (hydrochloride)
目录号:SY-123388
TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and α3β4 subunit-containing ganglionic nAChRs expressed in TE671/RD or SH-SY5Y cells. It inhibits nicotine-induced dopamine release from rat brain synaptosomes (IC50 = 480 nM). TMB 8 also reduces calcium availability in smooth and skeletal muscle, blocking the contractile response in isolated rabbit aortic strip when used at a concentration of 50 μM and inhibiting calcium influx and efflux in isolated guinea pig ileum when used at a concentration of 65 μM. It has been used in the study of intracellular calcium dynamics, particularly in smooth muscle. TMB 8 also inhibits protein kinase C (PKC) activity in a dose-dependent manner.
¥1078.00
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Zeorin
目录号:SY-123412
Zeorin shows strong inhibition activity against bacteria and fungi. It markedly exhibits inhibitory activity on histamine release from mast cell induced by DNP24-BSA, it shows potent inhibitory effect by 40% decrease of histamine release.
询价
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Sulcardine 2HCl
目录号:SY-123139
Sulcardine 2HCl 是一种多离子通道阻滞剂,具有抗心律失常作用,可阻断 hERG 和hNav1.5通道的特性,可用于研究心房颤动和室性心律失常。
¥1495.00
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L-Phenylalanine-13C
目录号:SY-123416
L-Phenylalanine-13C是一种具有 13C 标记的 L-Phenylalanine (T3377)。L-Phenylalanine ( (S)-2-Amino-3-phenylpropionic acid)是从大肠杆菌中提取的必需氨基酸,作为电压依赖性 α2δ 亚基 Ca2+ 通道的拮抗剂,其 Ki 为 980 nM。此外,L-Phenylalanine是NMDARs (Kᵦ 573 μM)和非NMDARs 甘氨酸和谷氨酸结合位点的竞争性拮抗剂,广泛应用于食品香料和药品的制造。
¥575.00
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Iganidipine
目录号:SY-123141
Iganidipine(NKY 722) 是一种新的水溶性 Ca2+ 拮抗剂,具有降压活性,可用于研究和神经系统相关的疾病。
¥14490.00
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Taurolithocholic acid sodium salt
目录号:SY-123149
Taurolithocholic acid sodium salt (Sodium taurolithocholate) 是抑胆剂和 Ca2+激动剂,可抑制放射性配体与毒蕈碱 M1 结合。
¥418.00
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