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Carpaine
目录号:SY-109298
Carpaine是一种具有抗疟活性的天然产物,在NL20 cell中对P. falciparum的IC50约为4μM。Carpaine具有心脏保护和抗炎作用,能够激活FAK、ERK1/2和AKT通路,抑制ROS产生。
¥3848.00
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MS5033
目录号:SY-109299
MS5033 是一种有效的基于 PROTAC 的 AKT 降解剂,在 PC3 细胞中的 DC50值为 430 nM。
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Isopropyl ferulate
目录号:SY-109300
Isopropyl ferulate 来源于羌活(Rhizoma et Radix Notopterygii)的活性物质,对 PANC-1 胰腺癌细胞具有显著细胞毒性,其 PC50 为 17.5 μg/mL。网络药理学分析提示其可调控 PI3K/Akt/mTOR、ErbB 与 IL-17 等信号通路,并在 IMQ 诱导及 LPS 刺激模型中获得验证,证明 Isopropyl ferulate 在癌症治疗研究中的重要意义。
¥172.00
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Nyasol
目录号:SY-109301
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antifungal activity, it is significantly
¥5985.00
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Isosativan
目录号:SY-109302
Isosativan是一种发现于Trifolium hybridum的天然产物,能够激活糖尿病大鼠mTORC2/AKT通路,抑制肌肉萎缩基因Atrogin-1和MuRF1。
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Arteanoflavone
目录号:SY-109303
Arteanoflavone is a natural product from Artemisia hispanica.
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CCT365623 hydrochloride
目录号:SY-109304
CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF.
¥1001.00
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Akt1 and Akt2-IN-1
目录号:SY-109305
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.
¥1232.00
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3-Deoxysappanchalcone
目录号:SY-109306
3-Deoxysappanchalcone is an effective HO-1 inducer at the translational level.
¥690.00
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